Nef functions in BLT mice to enhance HIV-1 replication and deplete CD4(+)CD8(+) thymocytes

BACKGROUND: The outcome of untreated HIV-1 infection is progression to AIDS and death in nearly all cases. Some important exceptions are the small number of patients infected with HIV-1 deleted for the accessory gene, nef. With these infections, disease progression is entirely suppressed or greatly...

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Bibliographic Details
Main Authors:	Zou, Wei, Denton, Paul W, Watkins, Richard L, Krisko, John F, Nochi, Tomonori, Foster, John L, Garcia, J Victor
Format:	Artigo
Language:	Inglês
Published:	BioMed Central 2012
Subjects:	Research
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3403983/ https://ncbi.nlm.nih.gov/pubmed/22640559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-9-44
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Nef functions in BLT mice to enhance HIV-1 replication and deplete CD4(+)CD8(+) thymocytes

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