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Nef functions in BLT mice to enhance HIV-1 replication and deplete CD4(+)CD8(+) thymocytes
BACKGROUND: The outcome of untreated HIV-1 infection is progression to AIDS and death in nearly all cases. Some important exceptions are the small number of patients infected with HIV-1 deleted for the accessory gene, nef. With these infections, disease progression is entirely suppressed or greatly...
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Huvudupphovsmän: | , , , , , , |
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Materialtyp: | Artigo |
Språk: | Inglês |
Publicerad: |
BioMed Central
2012
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Ämnen: | |
Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3403983/ https://ncbi.nlm.nih.gov/pubmed/22640559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-9-44 |
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