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In vivo analysis of highly conserved Nef activities in HIV-1 replication and pathogenesis
BACKGROUND: The HIV-1 accessory protein, Nef, is decisive for progression to AIDS. In vitro characterization of the protein has described many Nef activities of unknown in vivo significance including CD4 downregulation and a number of activities that depend on Nef interacting with host SH3 domain pr...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3907037/ https://ncbi.nlm.nih.gov/pubmed/24172637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-10-125 |
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