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Designing specific protein–protein interactions using computation, experimental library screening, or integrated methods
Given the importance of protein–protein interactions for nearly all biological processes, the design of protein affinity reagents for use in research, diagnosis or therapy is an important endeavor. Engineered proteins would ideally have high specificities for their intended targets, but achieving in...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Wiley Subscription Services, Inc., A Wiley Company
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3403433/ https://ncbi.nlm.nih.gov/pubmed/22593041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2096 |
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