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Designing specific protein–protein interactions using computation, experimental library screening, or integrated methods

Given the importance of protein–protein interactions for nearly all biological processes, the design of protein affinity reagents for use in research, diagnosis or therapy is an important endeavor. Engineered proteins would ideally have high specificities for their intended targets, but achieving in...

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Dettagli Bibliografici
Autori principali: Chen, T Scott, Keating, Amy E
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wiley Subscription Services, Inc., A Wiley Company 2012
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403433/
https://ncbi.nlm.nih.gov/pubmed/22593041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2096
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