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Computational toxicology methods in chemical library design and high-throughput screening hit validation

The discovery of molecular toxicity in a clinical drug candidate can have a significant impact on both the cost and timeline of the drug discovery process. Early identification of potentially toxic compounds during screening library preparation or, alternatively, during the hit validation process, i...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Autor principal: Hevener, Kirk E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6088382/
https://ncbi.nlm.nih.gov/pubmed/29934898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-7899-1_13
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