Nrf2 links epidermal barrier function with antioxidant defense

The skin provides an efficient permeability barrier and protects from microbial invasion and oxidative stress. Here, we show that these essential functions are linked through the Nrf2 transcription factor. To test the hypothesis that activation of Nrf2 provides skin protection under stress condition...

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Autores principales: Schäfer, Matthias, Farwanah, Hany, Willrodt, Ann-Helen, Huebner, Aaron J, Sandhoff, Konrad, Roop, Dennis, Hohl, Daniel, Bloch, Wilhelm, Werner, Sabine
Formato: Artigo
Lenguaje:Inglês
Publicado: WILEY-VCH Verlag 2012
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403295/
https://ncbi.nlm.nih.gov/pubmed/22383093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201200219
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