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Nrf2 links epidermal barrier function with antioxidant defense

The skin provides an efficient permeability barrier and protects from microbial invasion and oxidative stress. Here, we show that these essential functions are linked through the Nrf2 transcription factor. To test the hypothesis that activation of Nrf2 provides skin protection under stress condition...

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Autors principals: Schäfer, Matthias, Farwanah, Hany, Willrodt, Ann-Helen, Huebner, Aaron J, Sandhoff, Konrad, Roop, Dennis, Hohl, Daniel, Bloch, Wilhelm, Werner, Sabine
Format: Artigo
Idioma:Inglês
Publicat: WILEY-VCH Verlag 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403295/
https://ncbi.nlm.nih.gov/pubmed/22383093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201200219
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