Multifactorial pharmacogenetic analysis in colorectal cancer patients receiving 5-fluorouracil-based therapy together with cetuximab–irinotecan

AIM: To examine the predictive value of gene polymorphisms potentially linked to toxicity, clinical response, time to progression and overall survival, following cetuximab–tegafur-uracil (UFT)–irinotecan therapy. METHODS: Fifty-two patients with advanced colorectal cancer were enrolled in an ancilla...

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Bibliographic Details
Main Authors: Etienne-Grimaldi, Marie-Christine, Bennouna, Jaafar, Formento, Jean-Louis, Douillard, Jean-Yves, Francoual, Mireille, Hennebelle, Isabelle, Chatelut, Etienne, Francois, Eric, Faroux, Roger, El Hannani, Chaza, Jacob, Jacques-Henri, Milano, Gérard
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2012
Subjects:
Pharmacogenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403205/
https://ncbi.nlm.nih.gov/pubmed/22486600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2011.04141.x
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