Prospective analysis of the impact of VEGF-A gene polymorphisms on the pharmacodynamics of bevacizumab-based therapy in metastatic breast cancer patients

AIMS: To test prospectively the impact of VEGF-A gene polymorphisms on the pharmacodynamics of bevacizumab-chemotherapy in breast cancer patients. METHODS: As part of the single-arm MO19391 trial, 137 women with locally recurrent or metastatic breast cancer receiving first-line bevacizumab-containin...

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Hlavní autoři: Etienne-Grimaldi, Marie-Christine, Formento, Patricia, Degeorges, Armelle, Pierga, Jean-Yves, Delva, Rémi, Pivot, Xavier, Dalenc, Florence, Espié, Marc, Veyret, Corinne, Formento, Jean-Louis, Francoual, Mireille, Piutti, Magali, de Crémoux, Patricia, Milano, Gérard
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2011
Témata:
Pharmacogenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3099379/
https://ncbi.nlm.nih.gov/pubmed/21204912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2010.03896.x
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