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Pharmacogenetic profiling and cetuximab outcome in patients with advanced colorectal cancer
BACKGROUND: We analyzed the influence of 8 germinal polymorphisms of candidate genes potentially related to EGFR signalling (EGFR, EGF, CCND1) or antibody-directed cell cytotoxicity (FCGR2A and FCGR3A) on outcome of colorectal cancer (CRC) patients receiving cetuximab-based therapy. METHODS: Fifty-e...
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主要な著者: | , , , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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BioMed Central
2011
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オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3235081/ https://ncbi.nlm.nih.gov/pubmed/22117530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-496 |
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