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Modulation of cellular redox state underlies antagonism between oxaliplatin and cetuximab in human colorectal cancer cell lines

BACKGROUND AND PURPOSE: Oxaliplatin is the first platinum-based compound effective in the treatment of colorectal cancer. Oxaliplatin combined with cetuximab for metastatic colorectal cancer is under evaluation. The preliminary results seem controversial, particularly for the use of cetuximab in K-R...

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Detalhes bibliográficos
Main Authors: Dahan, Laetitia, Sadok, Amine, Formento, Jean-Louis, Seitz, Jean François, Kovacic, Hervé
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757701/
https://ncbi.nlm.nih.gov/pubmed/19732064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00341.x
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