Heparan Sulfate Enhances the Self-Renewal and Therapeutic Potential of Mesenchymal Stem Cells from Human Adult Bone Marrow

Insufficient cell number hampers therapies utilizing adult human mesenchymal stem cells (hMSCs) and current ex vivo expansion strategies lead to a loss of multipotentiality. Here we show that supplementation with an embryonic form of heparan sulfate (HS-2) can both increase the initial recovery of h...

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Detalhes bibliográficos
Main Authors: Helledie, Torben, Dombrowski, Christian, Rai, Bina, Lim, Zophia X.H., Hin, Ian Lee Hock, Rider, David A., Stein, Gary S., Hong, Wanjin, van Wijnen, Andre J., Hui, James H., Nurcombe, Victor, Cool, Simon M.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
Assuntos:
Original Research Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402859/
https://ncbi.nlm.nih.gov/pubmed/22066689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2011.0367
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