Heparan Sulfate Enhances the Self-Renewal and Therapeutic Potential of Mesenchymal Stem Cells from Human Adult Bone Marrow

Insufficient cell number hampers therapies utilizing adult human mesenchymal stem cells (hMSCs) and current ex vivo expansion strategies lead to a loss of multipotentiality. Here we show that supplementation with an embryonic form of heparan sulfate (HS-2) can both increase the initial recovery of h...

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Detaylı Bibliyografya
Asıl Yazarlar: Helledie, Torben, Dombrowski, Christian, Rai, Bina, Lim, Zophia X.H., Hin, Ian Lee Hock, Rider, David A., Stein, Gary S., Hong, Wanjin, van Wijnen, Andre J., Hui, James H., Nurcombe, Victor, Cool, Simon M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Mary Ann Liebert, Inc. 2012
Konular:
Original Research Reports
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402859/
https://ncbi.nlm.nih.gov/pubmed/22066689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2011.0367
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