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Combined Sphingosine, S1P and Ischemic Postconditioning Rescue the Heart after Protracted Ischemia

Both sphingosine and sphingosine 1-phosphate (S1P) were able to protect the ex vivo rat heart from ischemia reperfusion injury when added to the perfusion medium at the time of reperfusion after a 40 min ischemia (postconditioning). Inhibitor studies revealed distinct mechanisms of protection, with...

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Hlavní autoři: Vessey, Donald A., Li, Luyi, Kelley, Michael, Karliner, Joel S
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402379/
https://ncbi.nlm.nih.gov/pubmed/18706887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.08.022
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