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Combined Sphingosine, S1P and Ischemic Postconditioning Rescue the Heart after Protracted Ischemia
Both sphingosine and sphingosine 1-phosphate (S1P) were able to protect the ex vivo rat heart from ischemia reperfusion injury when added to the perfusion medium at the time of reperfusion after a 40 min ischemia (postconditioning). Inhibitor studies revealed distinct mechanisms of protection, with...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3402379/ https://ncbi.nlm.nih.gov/pubmed/18706887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.08.022 |
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