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Sphingosine Kinase and Sphingosine 1-Phosphate in the Heart: A Decade of Progress
Activation of sphingosine kinase/sphingosine 1-phosphate (SK/S1P) –mediated signaling has emerged as a critical cardioprotective pathway in response to acute ischemia/reperfusion injury. S1P is released in both ischemic pre- and post-conditioning. Application of exogenous S1P to cultured cardiac myo...
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3479372/ https://ncbi.nlm.nih.gov/pubmed/22735359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2012.06.006 |
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