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Autoantigen-Specific B-Cell Depletion Overcomes Failed Immune Tolerance in Type 1 Diabetes
Eliminating autoantigen-specific B cells is an attractive alternative to global B-cell depletion for autoimmune disease treatment. To identify the potential for targeting a key autoimmune B-cell specificity in type 1 diabetes, insulin-binding B cells were tracked within a polyclonal repertoire using...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Diabetes Association
2012
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3402296/ https://ncbi.nlm.nih.gov/pubmed/22698916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1746 |
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