IL-2/IL-2Ab Complexes Induce Regulatory T Cell Expansion and Protect against Proteinuric CKD

Regulatory T cells (Tregs) help protect against autoimmune renal injury. The use of agonist antibodies and antibody/cytokine combinations to expand Tregs in vivo may have therapeutic potential for renal disease. Here, we investigated the effects of administering IL-2/IL-2Ab complexes in mice with ad...

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Detalhes bibliográficos
Main Authors: Polhill, Tania, Zhang, Geoff Yu, Hu, Min, Sawyer, Andrew, Zhou, Jimmy Jianheng, Saito, Mitsuru, Webster, Kylie E., Wang, Ya, Wang, Yiping, Grey, Shane T., Sprent, Jonathan, Harris, David C.H., Alexander, Stephen I., Wang, Yuan Min
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2012
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402286/
https://ncbi.nlm.nih.gov/pubmed/22677553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011111130
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