CD8+ Regulatory T Cells Induced by T Cell Vaccination Protect Against Autoimmune Nephritis

Autoreactive T cells play a pivotal role in the pathogenesis of autoimmune kidney disease. T cell vaccination (TCV) may limit autoimmune disease and induce CD8+ regulatory T cells (Tregs). We used Heymann nephritis (HN), a rat model of human membranous nephritis, to study the effects of TCV on autoi...

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Detalhes bibliográficos
Main Authors: Wang, Yuan Min, Zhang, Geoff Yu, Hu, Min, Polhill, Tania, Sawyer, Andrew, Zhou, Jimmy Jianheng, Saito, Mitsuru, Watson, Debbie, Wu, Huiling, Wang, Ya, Wang, Xin Maggie, Wang, Yiping, Harris, David C.H., Alexander, Stephen I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2012
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358762/
https://ncbi.nlm.nih.gov/pubmed/22491420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011090914
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