CD8+ Regulatory T Cells Induced by T Cell Vaccination Protect Against Autoimmune Nephritis

Autoreactive T cells play a pivotal role in the pathogenesis of autoimmune kidney disease. T cell vaccination (TCV) may limit autoimmune disease and induce CD8+ regulatory T cells (Tregs). We used Heymann nephritis (HN), a rat model of human membranous nephritis, to study the effects of TCV on autoi...

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Autors principals: Wang, Yuan Min, Zhang, Geoff Yu, Hu, Min, Polhill, Tania, Sawyer, Andrew, Zhou, Jimmy Jianheng, Saito, Mitsuru, Watson, Debbie, Wu, Huiling, Wang, Ya, Wang, Xin Maggie, Wang, Yiping, Harris, David C.H., Alexander, Stephen I.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Nephrology 2012
Matèries:
Basic Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358762/
https://ncbi.nlm.nih.gov/pubmed/22491420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011090914
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