In vivo expansion of T reg cells with IL-2–mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression

Via a transcription factor, Foxp3, immunoregulatory CD4(+)CD25(+) T cells (T reg cells) play an important role in suppressing the function of other T cells. Adoptively transferring high numbers of T reg cells can reduce the intensity of the immune response, thereby providing an attractive prospect f...

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Bibliografske podrobnosti
Main Authors: Webster, Kylie E., Walters, Stacey, Kohler, Rachel E., Mrkvan, Tomas, Boyman, Onur, Surh, Charles D., Grey, Shane T., Sprent, Jonathan
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2009
Teme:
Brief Definitive Report
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715127/
https://ncbi.nlm.nih.gov/pubmed/19332874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20082824
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