NuRD Suppresses Pluripotency Gene Expression to Promote Transcriptional Heterogeneity and Lineage Commitment

Transcriptional heterogeneity within embryonic stem cell (ESC) populations has been suggested as a mechanism by which a seemingly homogeneous cell population can initiate differentiation into an array of different cell types. Chromatin remodeling proteins have been shown to control transcriptional v...

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Detalhes bibliográficos
Main Authors: Reynolds, Nicola, Latos, Paulina, Hynes-Allen, Antony, Loos, Remco, Leaford, Donna, O'Shaughnessy, Aoife, Mosaku, Olukunbi, Signolet, Jason, Brennecke, Philip, Kalkan, Tüzer, Costello, Ita, Humphreys, Peter, Mansfield, William, Nakagawa, Kentaro, Strouboulis, John, Behrens, Axel, Bertone, Paul, Hendrich, Brian
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402183/
https://ncbi.nlm.nih.gov/pubmed/22560079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2012.02.020
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