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Northern Ring Conformation of Methanocarba-Adenosine 5′-Triphosphate Required for Activation of P2X Receptors

[Table: see text] Replacement of the ribose moiety of adenosine 5′-triphosphate (ATP) with a carbocyclic ring constrained in either the Northern (N) or Southern (S) conformation produces agonists with widely differing activities at P2Y receptors (Kim et al. [2002] J Med Chem 45:208–218). We have use...

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Detalhes bibliográficos
Main Authors: Dunn, Philip M., Kim, Hak Sung, Jacobson, Kenneth A., Burnstock, Geoffrey
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402081/
https://ncbi.nlm.nih.gov/pubmed/22833693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ddr.10381
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