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Structure Activity Relationships for Derivatives of Adenosine-5′-Triphosphate as Agonists at P(2) Purinoceptors: Heterogeneity Within P(2X) and P(2Y) Subtypes

[Image: see text] The structure-activity relationships for a variety of adenine nucleotide analogues at P(2x)- and P(2Y)-purinoceptors were investigated. Compounds formed by structural modifications of the ATP molecule including substitutions of the purine ring (C2, C8, N1, and N(6)-substituents, an...

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Detalhes bibliográficos
Main Authors: Burnstock, Geoffrey, Fischer, Bilha, Hoyle, Charles H.V., Maillard, Michel, Ziganshin, Airat U., Brizzolara, Antonia L., von Isakovics, Amy, Boyer, José L., Harden, T. Kendall, Jacobson, Kenneth A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434461/
https://ncbi.nlm.nih.gov/pubmed/22962511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ddr.430310308
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