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Synthesis of a Novel Conformationally Locked Carbocyclic Nucleoside Ring System

[Image: see text] A fast and efficient synthetic route to novel Northern locked carbocyclic nucleosides (as precursors of carbocyclic locked nucleic acids or cLNAs) is described. The target nucleoside with a oxabicyclo[2.2.1]heptane ring system was prepared from a simple starting material, diethyl m...

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Autori principali: Kim, Hak Sung, Jacobson, Kenneth A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153471/
https://ncbi.nlm.nih.gov/pubmed/12735747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol034326z
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