Identification of allele-specific alternative mRNA processing via transcriptome sequencing

Establishing the functional roles of genetic variants remains a significant challenge in the post-genomic era. Here, we present a method, allele-specific alternative mRNA processing (ASARP), to identify genetically influenced mRNA processing events using transcriptome sequencing (RNA-Seq) data. The...

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Bibliografske podrobnosti
Main Authors: Li, Gang, Bahn, Jae Hoon, Lee, Jae-Hyung, Peng, Guangdun, Chen, Zugen, Nelson, Stanley F., Xiao, Xinshu
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2012
Teme:
Methods Online
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401465/
https://ncbi.nlm.nih.gov/pubmed/22467206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks280
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