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Accurate identification of A-to-I RNA editing in human by transcriptome sequencing

RNA editing enhances the diversity of gene products at the post-transcriptional level. Approaches for genome-wide identification of RNA editing face two main challenges: separating true editing sites from false discoveries and accurate estimation of editing levels. We developed an approach to analyz...

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Autores principales: Bahn, Jae Hoon, Lee, Jae-Hyung, Li, Gang, Greer, Christopher, Peng, Guangdun, Xiao, Xinshu
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246201/
https://ncbi.nlm.nih.gov/pubmed/21960545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.124107.111
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