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Allele-specific alternative splicing and its functional genetic variants in human tissues

Alternative splicing is an RNA processing mechanism that affects most genes in human, contributing to disease mechanisms and phenotypic diversity. The regulation of splicing involves an intricate network of cis-regulatory elements and trans-acting factors. Due to their high sequence specificity, cis...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Amoah, Kofi, Hsiao, Yun-Hua Esther, Bahn, Jae Hoon, Sun, Yiwei, Burghard, Christina, Tan, Boon Xin, Yang, Ei-Wen, Xiao, Xinshu
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7919445/
https://ncbi.nlm.nih.gov/pubmed/33452016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.265637.120
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