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Homologous recombination and its regulation

Homologous recombination (HR) is critical both for repairing DNA lesions in mitosis and for chromosomal pairing and exchange during meiosis. However, some forms of HR can also lead to undesirable DNA rearrangements. Multiple regulatory mechanisms have evolved to ensure that HR takes place at the rig...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Krejci, Lumir, Altmannova, Veronika, Spirek, Mario, Zhao, Xiaolan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401455/
https://ncbi.nlm.nih.gov/pubmed/22467216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks270
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