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Unloading of homologous recombination factors is required for restoring double‐stranded DNA at damage repair loci

Cells use homology‐dependent DNA repair to mend chromosome breaks and restore broken replication forks, thereby ensuring genome stability and cell survival. DNA break repair via homology‐based mechanisms involves nuclease‐dependent DNA end resection, which generates long tracts of single‐stranded DN...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Vasianovich, Yulia, Altmannova, Veronika, Kotenko, Oleksii, Newton, Matthew D, Krejci, Lumir, Makovets, Svetlana
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5239998/
https://ncbi.nlm.nih.gov/pubmed/27932447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201694628
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