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Real-time monitoring of RAG-catalyzed DNA cleavage unveils dynamic changes in coding end association with the coding end complex

During V(D)J recombination, the RAG1/2 recombinase is thought to play an active role in transferring newly excised recombination ends from the RAG post-cleavage complex (PCC) to the non-homologous end joining (NHEJ) machinery to promote appropriate antigen receptor gene assembly. However, this trans...

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Detalhes bibliográficos
Main Authors: Wang, Guannan, Dhar, Kajari, Swanson, Patrick C., Levitus, Marcia, Chang, Yung
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401440/
https://ncbi.nlm.nih.gov/pubmed/22434887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks255
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