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Critical amino acids in Escherichia coli UmuC responsible for sugar discrimination and base-substitution fidelity
The active form of Escherichia coli DNA polymerase V responsible for damage-induced mutagenesis is a multiprotein complex (UmuD′(2)C-RecA-ATP), called pol V Mut. Optimal activity of pol V Mut in vitro is observed on an SSB-coated single-stranded circular DNA template in the presence of the β/γ compl...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3401427/ https://ncbi.nlm.nih.gov/pubmed/22422840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks233 |
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