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Chronic activation of the kinase IKKβ impairs T cell function and survival
Activation of the transcription factor NF-κB is critical for cytokine production and T cell survival after T cell receptor (TCR) engagement. The effects of persistent NF-κB activity on T cell function and survival are poorly understood. In this study, using a murine model that expresses a constituti...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3401317/ https://ncbi.nlm.nih.gov/pubmed/22753932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102429 |
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