Regulation of T cell survival and mitochondrial homeostasis by TSC1

The mammalian target of rapamycin (mTOR) is a key regulator of cell growth and metabolism. It associates with multiple proteins and forms two distinct signaling complexes, mTORC1 and mTORC2. Accumulating evidence has revealed critical roles for intact mTOR signaling during T cell activation and resp...

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Bibliographische Detailangaben
Hauptverfasser: O’Brien, Thomas F., Gorentla, Balachandra K., Xie, Danli, Srivatsan, Sruti, McLeod, Ian X., He, You-Wen, Zhong, Xiao-Ping
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241742/
https://ncbi.nlm.nih.gov/pubmed/21805467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201141411
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