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Regulation of Transcription through Light-Activation and Light-Deactivation of Triplex-Forming Oligonucleotides in Mammalian Cells

Triplex-forming oligonucleotides (TFOs) are efficient tools to regulate gene expression through the inhibition of transcription. Here, nucleobase-caging technology was applied to the first temporal regulation of transcription through light-activated TFOs. Through site-specific incorporation of caged...

詳細記述

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書誌詳細
主要な著者: Govan, Jeane M., Uprety, Rajendra, Hemphill, James, Lively, Mark O., Deiters, Alexander
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401312/
https://ncbi.nlm.nih.gov/pubmed/22540192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb300161r
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