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Conditional Control of Alternative Splicing through Light-Triggered Splice-Switching Oligonucleotides

The spliceosome machinery is composed of several proteins and multiple small RNA molecules that are involved in gene regulation through the removal of introns from pre-mRNAs in order to assemble exon-based mRNA containing protein-coding sequences. Splice-switching oligo-nucleotides (SSOs) are geneti...

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Detaylı Bibliyografya
Yayımlandı:J Am Chem Soc
Asıl Yazarlar: Hemphill, James, Liu, Qingyang, Uprety, Rajendra, Samanta, Subhas, Tsang, Michael, Juliano, Rudolph L., Deiters, Alexander
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5545098/
https://ncbi.nlm.nih.gov/pubmed/25734836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b00580
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