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Conditional Control of Alternative Splicing through Light-Triggered Splice-Switching Oligonucleotides
The spliceosome machinery is composed of several proteins and multiple small RNA molecules that are involved in gene regulation through the removal of introns from pre-mRNAs in order to assemble exon-based mRNA containing protein-coding sequences. Splice-switching oligo-nucleotides (SSOs) are geneti...
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| Pubblicato in: | J Am Chem Soc |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5545098/ https://ncbi.nlm.nih.gov/pubmed/25734836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b00580 |
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