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Aptamer-Mediated Delivery of Splice-Switching Oligonucleotides to the Nuclei of Cancer Cells

To reduce the adverse effects of cancer therapies and increase their efficacy, new delivery agents that specifically target cancer cells are needed. We and others have shown that aptamers can selectively deliver therapeutic oligonucleotides to the endosome and cytoplasm of cancer cells that express...

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Detalhes bibliográficos
Main Authors: Kotula, Jonathan W., Pratico, Elizabeth D., Ming, Xin, Nakagawa, Osamu, Juliano, Rudolph L., Sullenger, Bruce A.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423875/
https://ncbi.nlm.nih.gov/pubmed/22703281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2012.0347
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