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Activation and Deactivation of DNAzyme and Antisense Function with Light for the Photochemical Regulation of Gene Expression in Mammalian Cells

The photochemical regulation of biological systems represents a very precise means of achieving high-resolution control over gene expression in both a spatial and a temporal fashion. DNAzymes are enzymatically active deoxyoligonucleotides that enable the site-specific cleavage of RNA, and have been...

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Detalhes bibliográficos
Main Authors: Young, Douglas D., Lively, Mark O., Deiters, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862549/
https://ncbi.nlm.nih.gov/pubmed/20392038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja100710j
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