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Stabilization and Photochemical Regulation of Antisense Agents through PEGylation
Oligonucleotides are effective tools for the regulation of gene expression in cell culture and model organisms, most importantly through antisense mechanisms. Due to the inherent instability of DNA antisense agents, various modifications have been introduced to increase the efficacy of oligonucleoti...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3207321/ https://ncbi.nlm.nih.gov/pubmed/21928851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc200411n |
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