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Cellular Delivery and Photochemical Activation of Antisense Agents through a Nucleobase Caging Strategy

Antisense oligonucleotides are powerful tools to regulate gene expression in cells and model organisms. However, a transfection or microinjection is needed for efficient delivery of the antisense agent. We report the conjugation of multiple HIV TAT peptides to a hairpin-protected antisense agent thr...

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Autori principali: Govan, Jeane M., Uprety, Rajendra, Thomas, Meryl, Lusic, Hrvoje, Lively, Mark O., Deiters, Alexander
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856437/
https://ncbi.nlm.nih.gov/pubmed/23915424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400293e
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