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Dual Targeting Antibacterial Peptide Inhibitor of Early Lipid A Biosynthesis
UDP-3-O-(R-3-hydroxyacyl)GlcN N-acyltransferase (LpxD) has been shown to be essential to survival of lipid A producing Gram-negative bacteria. In this study, LpxD-binding peptides 12 amino acids in length were identified from a phage-bound random peptide library screen. Three peptides displayed anti...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3401278/ https://ncbi.nlm.nih.gov/pubmed/22530734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb300094a |
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