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Enzymatic catalysis of anti-Baldwin ring closure in polyether biosynthesis

Polycyclic polyether natural products have fascinated chemists and biologists alike owing to their useful biological activity, highly complex structure and intriguing biosynthetic mechanisms. Following the original proposal for the polyepoxide origin of lasalocid and isolasalocid(1) and the experime...

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Detalhes bibliográficos
Main Authors: Hotta, Kinya, Chen, Xi, Paton, Robert S., Minami, Atsushi, Li, Hao, Swaminathan, Kunchithapadam, Mathews, Irimpan I., Watanabe, Kenji, Oikawa, Hideaki, Houk, Kendall N., Kim, Chu-Young
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401210/
https://ncbi.nlm.nih.gov/pubmed/22388816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10865
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