An Acenocoumarol Dosing Algorithm Using Clinical and Pharmacogenetic Data in Spanish Patients with Thromboembolic Disease

Appropriate dosing of coumarins is difficult to establish, due to significant inter-individual variability in the dose required to obtain stable anticoagulation. Several genetic and other clinical factors have been associated with the coumarins dose, and some pharmacogenetic-guided dosing algorithms...

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Detalhes bibliográficos
Main Authors: Borobia, Alberto M., Lubomirov, Rubin, Ramírez, Elena, Lorenzo, Alicia, Campos, Armando, Muñoz-Romo, Raul, Fernández-Capitán, Carmen, Frías, Jesús, Carcas, Antonio J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401172/
https://ncbi.nlm.nih.gov/pubmed/22911785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041360
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