A New Pharmacogenetic Algorithm to Predict the Most Appropriate Dosage of Acenocoumarol for Stable Anticoagulation in a Mixed Spanish Population

There is a strong association between genetic polymorphisms and the acenocoumarol dosage requirements. Genotyping the polymorphisms involved in the pharmacokinetics and pharmacodynamics of acenocoumarol before starting anticoagulant therapy would result in a better quality of life and a more efficie...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Tong, Hoi Y., Dávila-Fajardo, Cristina Lucía, Borobia, Alberto M., Martínez-González, Luis Javier, Lubomirov, Rubin, Perea León, Laura María, Blanco Bañares, María J., Díaz-Villamarín, Xando, Fernández-Capitán, Carmen, Cabeza Barrera, José, Carcas, Antonio J.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792430/
https://ncbi.nlm.nih.gov/pubmed/26977927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150456
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