Efficiency and effectiveness of the use of an acenocoumarol pharmacogenetic dosing algorithm versus usual care in patients with venous thromboembolic disease initiating oral anticoagulation: study protocol for a randomized controlled trial

BACKGROUND: Hemorrhagic events are frequent in patients on treatment with antivitamin-K oral anticoagulants due to their narrow therapeutic margin. Studies performed with acenocoumarol have shown the relationship between demographic, clinical and genotypic variants and the response to these drugs. O...

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Hlavní autoři: Carcas, Antonio J, Borobia, Alberto M, Velasco, Marta, Abad-Santos, Francisco, Díaz, Manuel Quintana, Fernández-Capitán, Carmen, Ruiz-Giménez, Nuria, Madridano, Olga, Sillero, Pilar Llamas
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
Study Protocol
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543328/
https://ncbi.nlm.nih.gov/pubmed/23237631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6215-13-239
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