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Pharmacogenetic-guided dosing of coumarin anticoagulants: algorithms for warfarin, acenocoumarol and phenprocoumon

Coumarin derivatives, such as warfarin, acenocoumarol and phenprocoumon are frequently prescribed oral anticoagulants to treat and prevent thromboembolism. Because there is a large inter-individual and intra-individual variability in dose–response and a small therapeutic window, treatment with couma...

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Detalhes bibliográficos
Main Authors: Verhoef, Talitha I, Redekop, William K, Daly, Ann K, van Schie, Rianne M F, de Boer, Anthonius, Maitland-van der Zee, Anke-Hilse
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971980/
https://ncbi.nlm.nih.gov/pubmed/23919835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12220
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