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Adenylyl Cyclase 2 Selectively Couples to E Prostanoid Type 2 Receptors, Whereas Adenylyl Cyclase 3 Is Not Receptor-Regulated in Airway Smooth Muscle

Adenylyl cyclases (ACs) are important regulators of airway smooth muscle function, because β-adrenergic receptor (βAR) agonists stimulate AC activity and cAMP production. We have previously shown in a number of cell types that AC6 selectively couples to βAR and these proteins are coexpressed in lipi...

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Autors principals: Bogard, Amy S., Adris, Piyatilake, Ostrom, Rennolds S.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400804/
https://ncbi.nlm.nih.gov/pubmed/22619251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.193425
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