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Role of the Intestinal Peptide Transporter PEPT1 in Oseltamivir Absorption: In Vitro and In Vivo Studies

It was reported that oseltamivir (Tamiflu) absorption was mediated by human peptide transporter (hPEPT) 1. Understanding the exact mechanism(s) of absorption is important in the context of drug-drug and diet-drug interactions. Hence, we investigated the mechanism governing the intestinal absorption...

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Main Authors: Poirier, Agnès, Belli, Sara, Funk, Christoph, Otteneder, Michael B., Portmann, Renée, Heinig, Katja, Prinssen, Eric, Lazic, Stanley E., Rayner, Craig R., Hoffmann, Gerhard, Singer, Thomas, Smith, David E., Schuler, Franz
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400791/
https://ncbi.nlm.nih.gov/pubmed/22584254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.112.044990
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