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Species-Dependent Uptake of Glycylsarcosine but Not Oseltamivir in Pichia pastoris Expressing the Rat, Mouse, and Human Intestinal Peptide Transporter PEPT1

The purpose of this study was to determine whether glycylsarcosine (a model dipeptide) and oseltamivir (an antiviral prodrug) exhibited a species-dependent uptake in yeast Pichia pastoris expressing the rat, mouse, and human homologs of PEPT1. Experiments were performed with [(3)H]glycylsarcosine (G...

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Bibliografski detalji
Glavni autori: Hu, Yongjun, Chen, Xiaomei, Smith, David E.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Pharmacology and Experimental Therapeutics 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382839/
https://ncbi.nlm.nih.gov/pubmed/22490229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.111.044263
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