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Species Differences in Human and Rodent PEPT2-Mediated Transport of Glycylsarcosine and Cefadroxil in Pichia Pastoris Transformants

The proton-coupled oligopeptide transporter PEPT2 (SLC15A2) plays an important role in the disposition of di/tripeptides and peptide-like drugs in kidney and brain. However, unlike PEPT1 (SLC15A1), there is little information about species differences in the transport of PEPT2-mediated substrates. T...

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Detalhes bibliográficos
Publicado no:Drug Metab Dispos
Main Authors: Song, Feifeng, Hu, Yongjun, Jiang, Huidi, Smith, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5267517/
https://ncbi.nlm.nih.gov/pubmed/27836942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.116.073320
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